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Journal of the Korean Society of Pediatric Nephrology ; : 128-131, 2014.
Article in English | WPRIM | ID: wpr-223752

ABSTRACT

Histopathologic evidence of "full-house" immune complex deposits is a pathognomonic feature of lupus nephritis. This report presents the case of a 12-year-old boy with persistent microscopic hematuria and proteinuria. He was diagnosed with "full-house" nephropathy based on a renal biopsy. However, there was no other clinical or biological evidence of systemic lupus erythematosus (SLE). Although the potential for isolated "full-house" nephropathy preceding SLE is unclear, such patients should be followed for clinical signs and autoantibodies of SLE. In most cases, microscopic hematuria has a good prognosis, and follow-up usually requires only regular urinalysis. However, we should be aware of isolated "full-house" nephropathy that remains asymptomatic for a long time, as few patients with no clinical signs and negative serology ultimately develop SLE.


Subject(s)
Child , Humans , Male , Antigen-Antibody Complex , Autoantibodies , Biopsy , Fluorescent Antibody Technique , Follow-Up Studies , Hematuria , Lupus Erythematosus, Systemic , Lupus Nephritis , Prognosis , Proteinuria , Urinalysis
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